Application Of Transgenic Animals Wikipedia
Transgenic animals are used to produce proteins which are important for medical and pharmaceutical applications.
Application of transgenic animals wikipedia. In medical research transgenic animals are used to identify the functions of specific factors in complex homeostatic systems through over- or under-expression of a modified gene the inserted transgene. The application of transgenic animals showed that within the next five to eight years genetically modified animals will play a significant and important role in the biomedical field in particular via the production of valuable pharmaceutical proteins and the supply of xenografts. Using transgenic mice as test systems eg protein CFTR secretion.
A transgenic animal is one that carries a foreign gene that has been deliberately inserted into its genome. Transgenic mice are used for testing the safety of vaccines. Theoretically all living beings can be genetically manipulated.
Transgenic animals are specially designed to study the role of genes in the development of certain diseases. The production of transgenic animals has focused mainly on producing models eg the mouse for basic and medical research. I to obtain information on gene function and regulation as well as on human diseases ii to obtain high value products recombinant pharmaceutica.
Sheep goats pigs cows rabbits rats mice fish insects parasites and even humans have previously been used in this modification process. The six applications are. 1 Resistance to Biotic Stresses 2 Resistance to Abiotic Stresses 3 Improvement of Crop Yield and Quality 4 Transgenic Plants with Improved Nutrition5 Commercial Transgenic Crop Plants and 6 Transgenic Plants as Bioreactors.
Transgenesis is the process by which mixing up of genes takes place. Many of these crosses of transgenic animals have these similar effects in the production of such products. This not only enables several human diseases to be cured but also make many people.
Applications of animal transgenesis may be divided into three major categories. However the realization of genetically engineered livestock has been much slower. Transgenic applications used in animals to enhance disease resistance include the transfer of major histocompatibility complex genes T-cell receptor genes and immunoglobulin genes.